Ongoing Studies

The Cancer Genomics Program has a number of studies that are currently recruiting patients. For information about how to be referred to one of these studies, please contact us.

Show studies of cancer.
Dr. Siu and Dr. Bedard meet with a patient to discuss the studies she is eligible for

Currently Recruiting

  • OCTANE

    Ontario-wide Targeted Nucleic Acid Evaluation

    Patients with the following cancers: Non-small cell lung, Colorectal, Malignant melanoma, Breast, Gynecological, Genitourinary, Pancreatobiliary,Gastrointestinal, Head and Neck, Unknown primary, Rare cancers

    Learn more(opens information in a pop-up overlay)
  • GENIUS

    Genomic Investigation of Unusual Responders

    Patients who have responded exceptionally well to a therapeutic drug or who were expected to respond favourable but displayed a poor outcome, with the following advanced cancer types: Breast, Colorectal, Non-small cell lung, Gynecological, Upper Aerodigestive Tract, Pancreatobiliary, Genitourinary, Unknown Primary, Rare Cancers

    Learn more(opens information in a pop-up overlay)
  • REFLECT

    Prospective Evaluation of Freshly Implanted Cancers in Mice to Test Drug Response in Matching Host

    Patients with the following cancer types: Triple negative breast cancer, Colorectal cancer, Other select tumour types (at the discretion of the Principle Investigator)

    Learn more(opens information in a pop-up overlay)
  • LIBERATE

    Liquid Biopsy Evaluation and Repository Development at Princess Margaret

    Patients with the following: Solid tumour, Hematological(pertaining to or originating from blood cells) malignancy , OR Patients identified as high-risk for cancer based on hormonal/family history without known aberration,Patients identified as high-risk for cancer based on identified aberration in cancer predisposition gene.

    Learn more(opens information in a pop-up overlay)
  • NET-SEQ

    Prospective Comprehensive Molecular Profiling In Neuroendocrine Tumors

    Patients with Neuroendocrine carcinomas

    Learn more(opens information in a pop-up overlay)
  • COM-PARISON

    Comprehensive Genomic Profiling of Colorectal Cancer Patients with Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy

    Patients with the following: colorectal cancer with isolated liver metastasis planned for hepatic metastasectomy, OR previous treatment with surgery for primary colorectal cancer with or without having received chemotherapy after surgery and are now diagnosed with isolated liver metastasis with plans for hepatic metastasectomy

    Learn more(opens information in a pop-up overlay)

Recruiting Soon

  • INSIGHT

    Integrative Sequencing in Germline and Hereditary Tumours

    Patients with the following: Multiple primary malignancies, Families with a strong family history of cancer suggestive of a hereditary cancer syndrome, Young individuals with cancer (10 years earlier than the age of onset of sporadic cases) and no identified gene mutation, Rare cancer histologies

    Learn more(opens information in a pop-up overlay)

Closed Recruiting

  • HPV-SEQ

    Genomic Analysis of HPV-related Lung Metastases from Head and Neck Cancers

    Patients with HPV-related neoplasms: Head and Neck, Lung

    Learn more(opens information in a pop-up overlay)
  • COMPACT

    Community Oncology Molecular Profiling in Advanced Cancers Trial

    Patients with the following advanced cancer types: Breast, Colorectal, Non-small cell lung, Gynecological, Upper Aerodigestive Tract, Pancreatobiliary, Genitourinary, Unknown Primary, Rare Cancers

    Learn more(opens information in a pop-up overlay)
  • I-IMPACT

    Immunoprofiling in IMPACT study

    Patients with any tumor type receiving immune therapies, such as those with the following cancer types Gynecological, Pancreatic, Head and Neck

    Learn more(opens information in a pop-up overlay)
  • IMPACT

    Integrated Molecular Profiling in Advanced Cancers Trial

    Patients with the following advanced cancer types: Breast, Colorectal, Non-small cell lung, Gynecological, Upper Aerodigestive Tract, Pancreatobiliary, Genitourinary, Unknown Primary, Rare Cancers

    Learn more(opens information in a pop-up overlay)
  • OCTOPUS

    Feasibility Clinical Study of Circulating Plasma DNA Analysis in Advanced Solid Tumor Patients

    Patients with the following advanced cancer types: Breast, Colorectal, Non-small cell lung, Gynecological, Upper Aerodigestive Tract, Pancreatobiliary, Genitourinary, Unknown Primary, Rare Cancers

    Learn more(opens information in a pop-up overlay)
  • MATCH

    A Feasibility Study of Genomic Profiling Methods and Timing of Sample Collection to Evaluate Clonal Evolution and Tumor Heterogeneity

    Patients with the following metastatic cancer types: Breast, Colorectal, Gynecological, Melanoma

    Learn more(opens information in a pop-up overlay)
  • SPECIAL

    Selection Pressure and Evolution induced by immune Checkpoint Inhibitors and other Immunologic Therapies

    Patients with the following: Multiple primary malignancies, Families with a strong family history of cancer suggestive of a hereditary cancer syndrome, Young individuals with cancer (10 years earlier than the age of onset of sporadic cases) and no identified gene mutation, Rare cancer histologies

    Learn more(opens information in a pop-up overlay)